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Manuel Pereira 

Dextromethorphan

Updated: May 28, 2023


(Image Source: Wikipedia)


Dextromethorphan

Dosage varies with each patient so use as directed on the label






Overview:

Dextromethorphan is a common cough syrup mixture that is used to suppress coughs.

Medical Uses:

This medication is used to provide short-term relief for coughs without phlegm which are caused by particular infections of the airway. It affects the signals in the brain that are responsible for triggering a cough reflex. While dextromethorphan works against standard coughs, do note that it will not be able to suppress coughs caused by smoking, asthma or emphysema.


Side-effects:

Serious side-effects include and are not limited to

  • Slight drowsiness

  • Stomach Upset


Drug interactions:

Do let your doctor know if you are taking any of these medications before starting Dextromethorphan. (Take note that this list is non-exhaustive)

  • Celecoxib

  • Cinacalcet

  • Darifenacin

  • Imatinib

  • Quinidine

  • Ranolazine

  • Ritonavir

  • Sibutramine

  • Terbinafine

  • High blood pressure medications

  • Antidepressant medications


Dosing:

Standard Recommended Dosing

Use as directed on the label. Do not give it to children under the age of 4. For the syrup version, typical dosage is 20mg every 4 hours as needed, but adhere to the max dosage of 120mg a day.


Overdosing

Seek emergency medical attention if you think you may have overdosed. A few symptoms of overdosing include

  • Anxiety, restlessness, severe dizziness

  • Convulsions or seizures

  • Confusion or Hallucinations

  • Slow, shallow breathing

  • Nausea

  • Panic

  • Mania

  • Extreme agitation

High doses may result in the patient becoming comatose or even resulting in death.


Notes:

  • This medication increases the depressant effect of alcohol on the Central Nervous System

  • It may also cause false-positives in urine drug testing for certain drugs

 

Citation:

Durbin, K. (2022, February 22). Dextromethorphan uses, dosage, side effects. Drugs.com. Retrieved February 5, 2023, from https://www.drugs.com/dextromethorphan.html#interactions


May, M. E. (n.d.). Dextromethorphan abuse. Poison Control. Retrieved February 5, 2023, from https://www.poison.org/articles/dextromethorphan


Team, C. by M. I. M. S. O. (n.d.). Dextromethorphan. Dextromethorphan: Indication, Dosage, Side Effect, Precaution | MIMS Singapore. Retrieved February 5, 2023, from https://www.mims.com/singapore/drug/info/dextromethorphan?mtype=generic


WebMD. (n.d.). Dextromethorphan cough oral: Uses, side effects, interactions, pictures, warnings & dosing. WebMD. Retrieved February 5, 2023, from https://www.webmd.com/drugs/2/drug-54288/dextromethorphan-cough-oral/details#:~:text=Slight%20drowsiness%2Fdizziness%2C%20nausea%2C,your%20doctor%20or%20pharmacist%20promptly.

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